Improving Detection Strategies for ATTR-CM

This technical report presents key takeaways from a roundtable discussion focused on improving the detection of transthyretin amyloid cardiomyopathy (ATTR-CM). The report outlines effective detection strategies, emphasizing the need for health systems to ensure consistent screening of heart failure patients with indicators of ATTR-CM while considering their capacity to manage increased patient volumes. Simplified clinical criteria are highlighted as essential for aligning health system leaders on when to suspect ATTR-CM. The report also discusses the importance of standardized care pathways tailored to the specific needs of health systems, which can enhance the patient journey from suspicion to diagnosis and treatment. High-quality imaging is identified as a critical factor in improving detection, necessitating strategies that address imaging reliability and interpretation. Additionally, the report underscores the foundational role of both provider and patient education in enhancing detection rates, although it notes that education alone is insufficient without supporting system strategies.