This case study details the successful implementation of Akselos Structural Performance Management (SPM) software by a North American refinery operator to enhance reactor uptime. The operator faced challenges with outdated procedures for cooling and heating heavy-walled reactors, which led to prolonged downtime and lost production. By adopting Akselos SPM, the refinery gained near real-time visibility into the stress and strain on their reactors during shutdown and startup processes. This allowed for faster cooldowns and startups while ensuring compliance with industry standards. The deployment of the software is projected to deliver an estimated return on investment of over 15 times within twelve months. The case study outlines how Akselos’ digital twin technology enabled the operator to reduce shutdown and startup times by up to 25%, thereby increasing production efficiency and optimizing inspection processes through targeted fatigue assessments. The operator chose Akselos for its ability to meet the demands of modern refinery operations.