This Performance Brief presents a detailed analysis of the 4th Gen AMD EPYC 9754 processors, focusing on their performance in cloud-native workloads. The document outlines the growing demand for cloud services and the challenges faced by service providers in scaling their infrastructure. It details the specifications of the AMD EPYC 9754 processors, including core count, cache size, memory support, and advanced features such as AVX-512 instruction support. The brief includes performance benchmarks comparing the AMD EPYC 9754 with top competitors, specifically the Intel Xeon Platinum 8490H and Ampere Altra Max CPUs, across various workloads including Server-Side Java, NGINX, Redis, and MySQL. The results indicate significant performance uplifts for the AMD EPYC 9754 in multiple scenarios, showcasing its capabilities in handling demanding cloud-native applications. The document also describes the test methodology and system configurations used for the benchmarks, ensuring clarity and reproducibility of the results.