Addressing Ischemia with Non-Obstructive Coronary Arteries

This document is a report discussing the critical health issue of Ischemia with Non-Obstructive Coronary Arteries (INOCA), particularly its impact on women. It outlines how cardiovascular disease is the leading cause of death among women in the United States and highlights the diagnostic challenges associated with INOCA. The report details the current limitations in diagnosing INOCA, including the inadequacy of standard non-invasive tools and the lack of education among primary care physicians regarding this condition. It emphasizes the need for a non-invasive, endotype-specific diagnostic tool that can be implemented earlier in the care pathway to improve patient outcomes. Furthermore, the report notes recent regulatory momentum, including increased reimbursement for AI-assisted diagnostic tools, which could facilitate the development of innovative solutions for INOCA. The document calls on investors to recognize the potential of INOCA diagnostics and to support advancements that can lead to better care for women suffering from this often-misunderstood condition.