Effective Approaches to Diagnostic Stewardship of Syndromic Molecular Panels

This review article presents effective approaches to diagnostic stewardship specifically for syndromic molecular panels used in the diagnosis of gastroenteritis, meningitis/encephalitis, and pneumonia. The article outlines the importance of diagnostic stewardship in ensuring appropriate test utilization and quality-assured results. It discusses the evolution of syndromic panels and their role in improving patient care and infection control while highlighting the potential risks associated with their indiscriminate use. The review details various phases of the diagnostic process where stewardship interventions can be applied, including preanalytic, analytic, and postanalytic phases. It emphasizes the need for a multidisciplinary approach involving clinicians, subspecialists, and clinical laboratories to optimize the use of these panels. The article also reviews specific use criteria and decision support tools that can enhance the accuracy and effectiveness of testing, ultimately leading to improved patient outcomes and resource utilization.