Improving mAb Purification Process Efficiency

This case study explores the efficiency of monoclonal antibody (mAb) purification processes using mixed-mode resins, specifically Nuvia aPrime 4A and CHT XT Media. It compares traditional three-step workflows to two-step processes, demonstrating higher yields and comparable purity. The study highlights the benefits of mixed-mode chromatography in improving process economics and reducing purification steps, making it a valuable resource for biopharmaceutical professionals seeking to optimize thei