Endoscopic Sleeve Gastroplasty Clinical Evidence Report

This document is a comprehensive clinical report on Endoscopic Sleeve Gastroplasty (ESG) as a primary endobariatric procedure for obesity management. It outlines the efficacy and safety of ESG, supported by a systematic literature review and meta-analysis of various studies. The report details the outcomes of ESG, highlighting significant weight loss results when combined with lifestyle modifications. It includes findings from multiple studies, including a prospective multicenter randomized trial and retrospective studies, showcasing the safety profile and effectiveness of ESG. The document also presents a position statement from the IFSO Bariatric Endoscopy Committee, emphasizing ESG's role in treating patients with class 1 and 2 obesity. Furthermore, it discusses the long-term outcomes of ESG, with follow-up data indicating sustained weight loss and improvements in obesity-related comorbidities over time. The report serves as a valuable resource for healthcare professionals involved in obesity management and endoscopic procedures.