This document is a technical report that outlines a comprehensive framework for integrating strategy and innovation methodologies. It presents a three-layered approach to understanding the complexities of new product strategy and business growth. The first layer focuses on defining and evaluating strategy hypotheses, emphasizing the need for coherence among various frameworks developed by thought leaders in the field. The second layer discusses the inner-loop methodology for innovation, detailing the iterative processes of hypothesizing, testing, and learning, alongside the outer-loop stage-gated investment decision-making. The third layer addresses portfolio strategy, highlighting the importance of tailored governance for explore and exploit work. The report synthesizes insights from established frameworks to provide a structured approach for innovation leaders to navigate the challenges of aligning strategy with execution, ensuring that all elements fit together cohesively for effective business growth.