Advancements in Immunopeptidomics Research at Broad Institute

This case study explores the innovative work of Dr. Claudia Ctortecka at the Broad Institute's Proteomics Platform, focusing on trapped ion mobility spectrometry (TIMS) to advance immunopeptidomics. The research aims to improve the identification and quantification of immunopeptides, facilitating breakthroughs in T cell-based therapies and understanding disease pathways. The study highlights challenges in sensitivity and sample input requirements, showcasing a high-throughput workflow for analyz