Evaluation of TXRF Spectrometer for Blood Analysis

This report evaluates the suitability of the TXRF spectrometer S2 PICOFOX for blood analysis, focusing on the analysis of essential and toxic elements in blood serum and whole blood. Part 1 describes the analysis of health-essential elements such as iron, chromium, manganese, nickel, copper, zinc, and selenium, emphasizing the importance of monitoring these elements to prevent deficiency diseases. The report discusses the feasibility of using Total Reflection X-ray Fluorescence (TXRF) spectroscopy for blood analysis without the need for time-consuming acid digestion methods. It details the sample preparation processes for both serum and whole blood, highlighting the simplicity and efficiency of TXRF. Part 2 addresses the analysis of platinum concentrations in blood samples of cancer patients undergoing chemotherapy, noting the critical need for precise monitoring due to the drug's toxicity. The report concludes that TXRF analysis provides accurate quantification of trace elements in blood samples, making it a valuable tool for both nutritional assessments and therapeutic monitoring.