CODEX Clinical Outcomes Database for Atopic Dermatitis

This brochure presents the CODEX Clinical Outcomes Database (ADERM), which compiles clinical trial outcomes data relevant to atopic dermatitis. The database consists of publicly available clinical trial data for marketed drugs and drugs in development, covering eight therapeutic areas and over sixty indications. It serves as a comprehensive repository of both structured and unstructured data, facilitating integration with internal datasets for modeling and simulation purposes. The brochure outlines the utility of the ADERM database across the drug development continuum, emphasizing its role in informing critical decisions regarding drug efficacy and competitive positioning. Additionally, it details the advantages of model-based meta-analysis (MBMA) in optimizing trial designs and enhancing drug development productivity. The document also highlights key efficacy and biomarker endpoints, alongside a landscape of systemic and novel pharmacological treatments for atopic dermatitis, thereby providing a detailed overview of the database's capabilities and applications in clinical research.