Characteristics and Applications of Isolation Valves

This white paper discusses the characteristics of three primary types of media isolation valves used in medical devices and analytical equipment: rocker isolation valves, diaphragm isolation valves, and pinch valves. It outlines the operational principles of each valve type and compares their advantages and disadvantages. Rocker isolation valves are noted for their compact size and cost-effectiveness but have higher dead volume and a shorter lifespan due to elastomeric seals. Diaphragm isolation valves offer longer life and better chemical compatibility, making them suitable for corrosive media. Pinch valves, while not formally classified as isolation valves, provide effective media isolation through disposable tubing and are particularly useful in applications requiring sterility. The paper emphasizes the importance of selecting the appropriate valve type based on application-specific requirements, including flow rate, pressure, and media compatibility. It also addresses lifetime considerations and operational reliability of these valves in medical applications.