This case study details the collaboration between a leading cancer center and ColorTokens to enhance cyber resiliency and mitigate risks associated with ransomware attacks. The cancer center, which operates multiple data centers and manages extensive data, faced challenges in securing its network infrastructure, particularly concerning backup administration and legacy systems. The document outlines the center's need for a Zero Trust architecture to protect sensitive patient data and critical applications, including the EMR system and radiation oncology application. ColorTokens implemented a Zero Trust microsegmentation strategy that allowed for improved visibility and control over network traffic while ensuring minimal disruption to existing operations. The approach included automatic policy recommendations and machine learning-based tagging, which facilitated rapid isolation of legacy systems. The results demonstrated a significant reduction in risk and operational downtime, enabling the cancer center to confidently manage its cybersecurity posture with the new solution.