This guide presents a framework for evaluating the sustainability of supply chains through a series of targeted questions. It outlines ten key areas to assess, including product design, production management, reverse logistics, and the use of data and technology. Each area includes specific questions that help organizations identify their current practices regarding sustainability. The guide emphasizes the importance of using renewable materials, modular designs, AI-powered demand forecasting, and product lifecycle management tools. It also discusses the role of IoT devices and predictive analytics in optimizing supply chain efficiency. Additionally, the guide provides scoring criteria to help organizations gauge their sustainability efforts and suggests next steps based on their scores. These steps range from laying the foundations for sustainability to evolving strategies and staying ahead of technological advancements. The guide aims to assist businesses in enhancing their supply chain operations while meeting growing customer demands for environmentally friendly products.