Global Enrollment Strategies in COPD Clinical Trials

This case study outlines the collaboration between Fortrea and a European sponsor to enhance the clinical development of respiratory drugs, specifically targeting Chronic Obstructive Pulmonary Disease (COPD). It details how the partnership utilized a supportive governance structure and tailored solutions to achieve recruitment goals ahead of target. Notably, one study experienced an over 80% increase in recruitment rates in the U.S. The document describes various strategies employed, including leveraging advanced technology platforms for operational oversight, centralized data monitoring, and predictive enrollment insights. These initiatives enabled early risk identification and optimization of site performance, contributing to high data integrity. The case study also addresses the challenges faced in recruiting patients for large-scale clinical trials, such as regulatory complexities and variations in standard care treatments across countries. The conclusion highlights the successful outcomes of the initiatives, including significant cycle-time reductions and strong site relationships, which facilitated achieving global enrollment ahead of schedule.