This document is a strategic guide outlining a comprehensive approach to promote artificial intelligence (AI) in scientific research across Europe. It emphasizes the importance of collaboration among European research actors to create a unified AI strategy that enhances efficiency and innovation. The guide details five key pillars necessary for achieving this vision: fostering shared infrastructure, improving shared knowledge, integrating a shared improvement process, investing in AI skills for science, and empowering shared innovation from AI research. Each pillar is designed to address specific needs, such as creating a common platform for data and computing resources, establishing a network for continuous education, and ensuring responsible AI usage through unified governance frameworks. The document also highlights the need for interdisciplinary collaboration and the support of research-based start-ups to translate AI advancements into practical applications. By implementing these strategies, the guide aims to strengthen Europe's position in the global scientific landscape and enhance the impact of AI on research and society.