This white paper presents a comprehensive checklist for mobile threat defense, detailing various threats against mobile devices and strategies for mitigation. It begins by outlining the types of threats, including malware, mobile ransomware, unsecured Wi-Fi networks, and phishing attacks. The document emphasizes the importance of a robust mobile threat defense mechanism to protect sensitive data and maintain organizational trust. Key areas of focus include connectivity, management, and security, highlighting the need for secure network infrastructure and effective mobile device management policies. The paper also discusses the implementation of endpoint protection solutions, real-time monitoring, and employee training to enhance mobile security. Furthermore, it describes the integration of mobile threat defense with Unified Endpoint Management (UEM) solutions, which provide a unified approach to managing and securing all endpoint devices. The checklist aims to assist organizations in reducing the risk of mobile-related cyberattacks and ensuring compliance with industry regulations.