Microbial Genomics Applications of MiSeq i100 Plus System

This document is a technical report discussing the use of the MiSeq i100 Plus System and MiSeq i100 Series Reagent Kit (1000 cycles) at the University of Zurich Institute of Medical Microbiology. The report outlines the institute's research focus on microbial genomics, particularly in the context of next-generation sequencing (NGS). Dr. Helena Seth-Smith, co-lead of the Microbial Genomics Division, describes her role and the applications of NGS in identifying and classifying microbial species. The report details ongoing research projects, including studies on chlamydia and Mycobacterium tuberculosis, and highlights the advantages of using the MiSeq i100 Plus System for generating high-quality genomic data. The document emphasizes the system's capabilities in improving turnaround times and reducing costs, which are critical for clinical and research applications. Additionally, it discusses the potential future applications of the MiSeq system in microbiome research and the characterization of isolates.