Residual Gas Analysis in Pharmaceutical Freeze-Drying

This application note discusses the use of Residual Gas Analysis (RGA) in monitoring the decomposition of thermally sensitive materials during freeze-drying in the pharmaceutical industry. It highlights the integration of the INFICON Transpector CPM 3 with a freeze-dryer to optimize the process and ensure the stability of active pharmaceutical ingredients. The findings demonstrate the importance of precise gas composition monitoring for successful formulation development.