This document is a solution note detailing the Infoblox Protective DNS (PDNS) offering. It outlines the increasing threat of cybercrime, with projected global costs reaching $23 trillion by 2027, and the critical role of PDNS in addressing these threats. The note explains how PDNS serves as a control point to analyze DNS queries and block various cyber threats, including malware and ransomware. It emphasizes the importance of proactive security strategies that identify and mitigate threats before they impact networks. The document also discusses the validation of PDNS by government agencies, including the UK’s NCSC and the U.S. CISA, and highlights the capabilities of Infoblox Threat Defense, which leverages predictive threat intelligence and machine learning to enhance security. Key benefits include early detection of threats, automation of threat response, and improved operational efficiency for security teams. The note concludes with insights into the protection of cloud workloads and IoT systems, emphasizing the comprehensive nature of the Infoblox solution.