This guide explains the importance of structure when selecting Exchange-Traded Funds (ETFs). It outlines the two primary replication methods used by ETFs: physical and synthetic. Physical ETFs buy and hold a basket of securities that closely matches the index, while synthetic ETFs use swap contracts to deliver index performance. The document details the risks associated with synthetic ETFs, particularly counterparty risk, and discusses how ETF providers can mitigate these risks through careful selection of securities and counterparties. Additionally, it presents various factors influencing the choice between synthetic and physical replication, including tax treatment, costs, and market dynamics. The guide emphasizes that both replication methods have their advantages and disadvantages, suggesting that investors should consider their specific needs and market conditions when selecting ETFs. The document concludes by highlighting the evolving landscape of ETF investment strategies, where investors are increasingly adopting a balanced approach to both replication methods.