Overcoming Barriers to Clinical Trial Participation in Oncology

This technical report addresses the challenges associated with recruiting and retaining patients for clinical trials in oncology. It outlines various barriers to participation, including patient awareness, misconceptions about clinical trials, and logistical issues such as travel and eligibility criteria. The report highlights the significance of Home Trial Support and community-focused Site Networks in enhancing patient experience and reducing burdens associated with trial participation. It details how decentralized clinical trial designs can improve access to novel treatments, particularly for underserved populations. The report also discusses the impact of the COVID-19 pandemic on clinical trial participation and emphasizes the need for community-based models to facilitate recruitment and retention. By leveraging local healthcare providers and offering flexible scheduling, these models aim to democratize clinical trial participation and improve patient outcomes. Overall, the report presents a comprehensive view of the current landscape of oncology clinical trials and potential solutions to overcome existing barriers.