Systematic Review of BPC-157 in Sports Medicine

This document is a systematic review that synthesizes the literature on Body Protective Compound 157 (BPC-157) in the context of orthopedic sports medicine applications. The review examines the regenerative potential of BPC-157, which is a gastric peptide increasingly used by athletes for musculoskeletal healing. The review outlines the methodology, including a comprehensive search of English-language literature from databases such as PubMed and Cochrane, adhering to PRISMA guidelines. A total of 39 articles were included, detailing BPC-157's mechanisms of action, musculoskeletal effects, and safety profiles. The findings indicate that BPC-157 may enhance recovery in various musculoskeletal injuries, although its safety in humans remains unverified. The review concludes with a cautionary note regarding the use of BPC-157 due to the lack of high-quality clinical evidence and calls for further research to validate its effects and safety in clinical settings.