This guide provides essential information for managing survey risk related to significant medication errors in Long Term Care Facilities (LTCFs). It outlines the definition of significant medication errors, which are those that cause discomfort or jeopardize the health and safety of residents. The document details how surveyors assess the significance of medication errors based on resident condition, drug category, and frequency of errors. It explains when errors are cited, emphasizing the importance of observation and documentation. The guide identifies high-risk medications that are prone to significant errors, including phenytoin, warfarin, and various classes of drugs such as antipsychotics and anticoagulants. It also discusses common types of medication errors, including omissions, unauthorized medications, and wrong dosages. The document highlights the need for accurate documentation and adherence to medication administration guidelines to minimize survey risk and ensure resident safety.