ISPOR Europe 2025 Report on Health Economics Trends

This report presents findings from the ISPOR Europe 2025 conference held in Glasgow, Scotland, from November 9 to 12, 2025. The document outlines key themes identified during the event, focusing on health economics and outcomes research (HEOR). It details the importance of applying learnings from early joint clinical assessments to enhance EU HTA submission readiness and emphasizes the necessity of decision-grade real-world evidence to satisfy regulatory and HTA agency requirements. Additionally, the report discusses the growing demand for rigorous health economic modeling to support reimbursement dossiers. The document also includes insights into the utilization of generative AI and large language models in qualitative data analysis, the role of real-world data in regulatory decisions, and the significance of incorporating patient perspectives into HTA submissions. Overall, the report serves as a comprehensive summary of the major trends and insights shared at the conference, providing valuable information for stakeholders in the HEOR field.