Enhancing mRNA Capture with Resolute BioSMB and CIMmultus Oligo dT

This case study explores the application of Resolute® BioSMB for continuous mRNA capture chromatography using CIMmultus® Oligo dT monoliths. It highlights the efficiency and scalability of integrated continuous bioprocessing, demonstrating a 57% increase in productivity and high yields of 97%. The study emphasizes the advantages of multi-column chromatography (MCC) in bioprocessing, particularly in response to the growing demand for effective drug substances post-COVID-19.