Use of Lyophilized Dehydrated Human Placental Membrane Allograft

This case report describes the application of a lyophilized dehydrated complete human placental membrane (dCHPM) allograft for wound bed preparation in a patient with a severe foot injury resulting from a motor vehicle accident. The patient, a healthy 32-year-old male, presented with a necrotic wound six weeks post-injury, following a partial first ray amputation. Initial treatment involved serial debridement and subsequent application of the dCHPM allograft. The wound preparation included sharp debridement and placement of three allografts, which were noted to withstand suturing and function effectively under a negative pressure wound vacuum. One week after the allograft application, significant improvement was observed, with an increase in granulation tissue coverage from 40% to 90%. A split-thickness skin graft (STSG) procedure was performed, resulting in complete resolution of the wound within three weeks. This report documents the clinical outcomes and procedural details associated with the use of dCHPM in traumatic wound care.