This white paper provides a comprehensive framework for implementing responsible artificial intelligence (AI) practices within organizations. It outlines the growing importance of responsible AI in mitigating technology risks, particularly in light of recent advancements in AI technologies such as Generative AI and large language models. The document emphasizes that responsible AI is not solely about ethical considerations but encompasses governance, accountability, compliance, and operational efficiency. It details three key themes central to responsible AI: governance, ethics, and efficiency, which together form the foundational pillars necessary for effective AI deployment. The paper also discusses the necessity of establishing a governance framework that includes risk management and accountability to ensure ethical AI practices are integrated throughout the AI lifecycle. Additionally, it highlights the role of tools like ClearScape Analytics™ and ModelOps in facilitating the governance and compliance of machine learning models, ultimately fostering trust among stakeholders and enhancing organizational transparency.