Blood Culture Systems for Pathogen Identification and Testing

This technical report outlines the landscape of simplified and integrated systems for pathogen identification and antimicrobial susceptibility testing, particularly in the context of antimicrobial resistance (AMR). It emphasizes the critical need for effective surveillance of AMR, especially in low-resource settings where laboratory capacity is often inadequate. The report identifies and evaluates 26 technologies that have been developed to address these challenges, focusing on their capabilities for blood culture and antimicrobial susceptibility testing. The assessment methodology is based on established guidelines, and the results highlight the top technologies that meet specific criteria for effectiveness. The report also discusses the implications of recent international initiatives aimed at combating AMR and the ongoing innovation in diagnostic technologies. Furthermore, it provides a comparison of key platforms and their attributes, along with recommendations for continued monitoring of these technologies as they evolve. The findings aim to inform stakeholders about the advancements in diagnostic tools that can enhance patient care and inform treatment strategies in resource-limited environments.