This document is a guide that outlines the critical importance of clinical communication and collaboration (CC&C) platforms for hospitals facing cyberattacks. It explains how hospitals are increasingly targeted due to the sensitive data they hold, which can lead to significant disruptions in patient care and operational continuity. The guide details the alarming statistics regarding cyberattacks in healthcare, emphasizing the need for hospitals to prepare effectively. It presents strategies for maintaining communication during a crisis, including the necessity of having systems that are independent of electronic health records (EHR) and capable of mass communication. The document also emphasizes the importance of immediate response activation to minimize damage to clinical workflows and patient safety. Additionally, it discusses the benefits of CC&C platforms in streamlining operations even during routine days, ultimately advocating for preparedness against potential cyber threats to ensure continuous care delivery.