This guide outlines the ACT Instant AI ad testing methodology developed by Toluna, which utilizes synthetic personas created from first-party panel data. The system aims to deliver fast and validated testing results for advertising campaigns, particularly in high-stakes environments such as the Super Bowl. The personas are designed to reflect human emotional responses, allowing for a nuanced understanding of ad effectiveness. The document explains the setup process, which can be completed in minutes, and the standardized key performance indicators (KPIs) employed to benchmark results across different countries and ad formats. Key findings demonstrate that the synthetic personas' responses closely align with human reactions, emphasizing aspects such as attention, brand recall, and emotional resonance. The methodology has been validated against human test scores, achieving up to 85% predictive accuracy in classifying ads as strong or weak performers. This framework provides clients with essential outputs for data-driven decision-making regarding their advertising strategies.