Performance Comparison of ACQUITY Premier Fixed-Loop Systems

This application note presents a performance comparison between the ACQUITY Premier Fixed-Loop System and the ACQUITY UPLC I-Class PLUS Fixed-Loop System. It highlights the benefits of MaxPeak™ High Performance Surfaces (HPS) Technology in reducing metal interactions for metal-sensitive analytes, demonstrating improved peak shape and area reproducibility. Key performance metrics such as peak tailing, height, and retention time precision are analyzed, showcasing the advantages of the ACQUITY Prem