This guide details the implementation specifications of Wazuh for compliance with HIPAA regulations. It outlines the security management processes required for covered entities and business associates, emphasizing the need for policies and procedures to prevent, detect, contain, and correct security violations. The guide describes the risk analysis process, which involves assessing potential risks and vulnerabilities to electronic protected health information. It also covers the configuration assessment and vulnerability detection capabilities of the Wazuh modules, which help ensure compliance with security hardening policies. Additionally, the document explains the importance of workforce security, including access management and termination procedures, to safeguard electronic protected health information. The guide further discusses the necessity of implementing security awareness training and incident response procedures to address security incidents effectively. Overall, it serves as a comprehensive resource for organizations seeking to utilize Wazuh to meet HIPAA compliance requirements.