Performance Evaluation of NovaPure Plungers in Autoinjectors

This technical report presents the performance evaluation of West's NovaPure® plungers designed for use in pre-filled syringes and autoinjector systems. The study compares the performance of 1-3mL and 1mL Long NovaPure® plungers against standard plungers over a 12-month period using various viscosity solutions representative of common biologic drug formulations. Key performance metrics assessed include delivered volume accuracy, injection time, break loose and glide force (BLG), and work of extrusion. Results indicate that NovaPure® plungers exhibit equivalent or superior performance in all tested aspects compared to standard plungers, showing faster injection times and lower energy requirements for operation. The report emphasizes the importance of selecting high-quality components for enhancing the performance of autoinjector applications, particularly as drug manufacturers transition to more convenient delivery systems. The findings support the suitability of NovaPure® plungers in meeting the demands of modern drug delivery systems.