Sex-based Outcomes Following Thoracic Endovascular Aortic Repair

This meta-analysis examines sex-based outcomes following thoracic endovascular aortic repair (TEVAR) for acute complicated type B aortic dissection (TBAD). The objective is to evaluate the impact of sex on primary and secondary outcomes by comparing male and female cohorts undergoing TEVAR. A systematic search identified five studies involving 2572 patients, with the primary outcome being hospital mortality and secondary outcomes including reintervention rates, acute kidney injury (AKI), ischemic stroke, limb ischemia, and spinal cord ischemia. The analysis reveals that there is no significant difference in hospital mortality between males and females. However, males exhibit a significantly higher risk of AKI. The findings suggest that while most clinical outcomes are comparable between sexes, male patients face an increased risk of postoperative complications. Future research is recommended to explore mechanisms and strategies to optimize outcomes for patients undergoing TEVAR.