Adenoid Cystic Carcinoma Treated With ZAP-X Radiosurgery

This document is a case report detailing the treatment of recurrent adenoid cystic carcinoma (ACC) in elderly patients using the ZAP-X Gyroscopic Radiosurgery System. It presents two cases of elderly female patients, aged 84 and 89, who were treated with salvage ZAP-X radiosurgery after previous treatment failures. The first patient had a recurrent lesion in the nasopharynx, and the second had a larger tumor in the nasal cavity and ethmoid sinus. The report outlines the treatment planning process, including MRI-based simulations and the specific dosages administered. Both patients tolerated the treatment well, with no significant toxicities reported. Follow-up results indicated significant tumor reduction in the first patient and disease stabilization in the second. The findings suggest that ZAP-X radiosurgery is a feasible and effective option for managing recurrent ACC in elderly patients, particularly in complex anatomical locations. The report advocates for further studies to validate these initial findings and explore the long-term outcomes of this treatment approach.